The Low-Threshold Calcium Channel Cav3.2 Determines Low-Threshold Mechanoreceptor Function
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چکیده
منابع مشابه
A silicon implementation of the thalamic low threshold calcium current
A silicon model of the thalamic low threshold calcium current is presented. The channel current (IT) is the product of an activation and inactivation current, normalized by their sum. The individual currents are modeled by a simple current-mirror integrator circuit. A modified differential pair controls the threshold of activation while a leak transistor added to the inactivation mirror control...
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It has been suggested that primary afferent C-fibres that respond to innocuous tactile stimuli are important in the sensation of pleasurable touch. Although it is known that C-tactile fibres terminate in the substantia gelatinosa (lamina II) of the spinal cord, virtually all of the neurons in this region are interneurons, and currently it is not known how impulses in C-mechanoreceptors are tran...
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[email protected] An Erbium:Ytterbium codoped microcavity-based laser which is lithographically fabricated from sol-gel is demonstrated. Both single-mode and multimode lasing is observed in the C band (1550nm). The quality factor and pump threshold are experimentally determined for a series of erbium and ytterbium doping concentrations, verifying the interdependent relationship between the two dop...
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The low-threshold calcium current, or T current, has recently been demonstrated with voltage-clamp recordings in a variety of central nervous system (CNS) neurons. It is especially prominent in the soma and dendrites of neurons with robust calcium-dependent burst firing behaviors such as thalamic relay neurons and cerebellar Purkinje cells. Single-channel and macroscopic current behavior have b...
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ژورنال
عنوان ژورنال: Cell Reports
سال: 2015
ISSN: 2211-1247
DOI: 10.1016/j.celrep.2014.12.042